SELECTED PUBLICATIONS
MacLauchlan S, Kushwaha P, Tai AK, Chen J, Manning C, Swarnkar G, Abu-Amer Y, Fitzgerald KA, Sharma S, Gravallese, EM (2023). Sting-dependent Interferon Signatures Restrict Osteoclast Differentiation and Bone Loss In Mice. Proc. Natl. Acad. Sci. U.S.A., 15(120). PubMed
Stavre Z, Kim J, Yang Y, Nündel K, Chaugule S, Sato T, Park KH, Gao G, Gravallese EM, Shim, JH. (2023). Schnurri-3 Inhibition Suppresses Bone and Joint Damage In Models Of Rheumatoid Arthritis. Proc. Natl. Acad. Sci. U.S.A., 19(120). PubMed
Yang YS, Xie J, Wang D, Kim JM, Tai PWL, Gravallese EM, Gao G, Shim JH. Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis. Nat Commun. 2019 Jul 4;10(1):2958. PubMed
Gravallese EM, Schett G. Effects of the IL-23-IL-17 pathway on bone in spondyloarthritis. Nat Rev Rheumatol. 2018 Nov;14(11):631-40. PubMed
Solomon DH, Kay J, Duryea J, Lu B, Bolster MB, Yood RA, Han R, Ball S, Coleman C, Lo E, Wohlfahrt A, Sury M, Yin M, Yu Z, Zak A, Gravallese EM. Effects of Teriparatide on joint erosions in rheumatoid arthritis: A randomized controlled trial. Arthritis Rheum. 2017 Sep;69(9):1741-50. PubMed
Maeda Y, Farina NH, Matzelle MM, Fanning PJ, Lian JB, Gravallese EM. Synovium-derived microRNAs regulate bone pathways in rheumatoid arthritis. J Bone Miner Res. 2017 Mar;32(3):461-472. PubMed
Baum R, Sharma S, Organ JM, Jakobs C, Hornung V, Burr DB, Marshak-Rothstein A, Fitzgerald KA, Gravallese EM. STING contributes to abnormal bone formation induced by deficiency of DNase II in mice. Arthritis Rheumatol. 2017 Feb;69(2):460-471. PubMed
Shaw AT, Maeda Y, Gravallese EM. IL-17A deficiency promotes periosteal bone formation in a model of inflammatory arthritis. Arthritis Res Ther. 2016; 18:104. PubMed
Baum R, Sharma S, Carpenter S, Li QZ, Busto P, Fitzgerald KA, Marshak-Rothstein A, Gravallese EM. Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice. J Immunol. 2015 Feb 1;194(3):873-7. PubMed
Matzelle MM, Gallant MA, Condon KW, Walsh NC, Manning CA, Stein GS, Lian JB, Burr DB, Gravallese EM. Resolution of inflammation induces osteoblast function and regulates the Wnt signaling pathway. Arthritis Rheum. 2012 May;64(5):1540-50. PubMed
Walsh NC, Reinwald S, Manning CA, Condon KW, Iwata K, Burr DB, Gravallese EM. Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis. J Bone Miner Res. 2009 Sep;24(9):1572-85. PubMed
Pettit AR, Ji H, von Stechow D, Müller R, Goldring SR, Choi Y, Benoist C, Gravallese EM. TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am J Pathol. 2001 Nov;159(5):1689-99. PubMed
Gravallese EM, Manning C, Tsay A, Naito A, Pan C, Amento E, Goldring SR. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum. 2000 Feb;43(2):250-8. PubMed